Solid dosage forms and oral liquids

Tablet and oral liquid calculations

How to calculate the number of tablets and the mL of an oral liquid, and what to consider with splitting and modified-release products.

Tablets

Work out the number of tablets from the dose and the strength.

Number of tablets = Prescribed dose ÷ Strength per tablet
Worked example: Prescribed 150 mg, 50 mg tablets. 150 ÷ 50 = 3 tablets.
Good to know: Only split tablets that are designed to be split (scored tablets). Modified-release, prolonged-release and enteric-coated tablets should normally not be split or crushed, because that changes how the drug is released. Always check the product information and follow local policy.

Oral liquids and drops

The strength is often given in mg/mL.

Amount (mL) = Prescribed dose ÷ Strength (mg/mL)
Worked example: Prescribed 200 mg, liquid 40 mg/mL. 200 ÷ 40 = 5 mL.

The number of drops per mL varies between products, so use the figure given in the question or in the product information. Amounts are measured with an oral syringe or dosing cup, not with household spoons.

01

Read the strength

Is it given in mg/mL, mg/5 mL or as a percentage?

02

Convert to the same unit

The dose and the strength must be in the same unit before you divide.

03

Check the answer

Is the amount sensible to give? A very large or very small amount is a warning sign.

More on calculations can be found in the dosage calculator and the DSM triangle.

Frequently asked questions

How do you calculate the number of tablets?+

Divide the prescribed dose by the strength per tablet.

Can all tablets be split?+

No. Only split tablets that are designed for it. Modified-release and enteric-coated tablets should normally not be split or crushed. Check the product information.

How do you calculate the mL of an oral liquid?+

Divide the dose by the strength in mg/mL.

How many drops are in a mL?+

It varies between products. Use the figure in the product information or the question.

See all the drug calculation formulas →

Practise tablets and liquids

Practise calculating the number of tablets and mL in practice questions, with the calculator next to each question. Dos is a practice app for drug calculations, with practice tests of ten questions, a built-in calculator next to each question and statistics per topic.