Infusions — drug calculations

Infusion rate: how to calculate mL per hour

The infusion rate formula with examples, a calculator and how to calculate when the dose is given per kg per minute.

The infusion rate formula

The rate is the volume divided by the time.

Rate (mL/h) = Volume (mL) ÷ Time (hours)
Worked example: 500 mL is to be given over 4 hours. Rate = 500 ÷ 4 = 125 mL/hour.

If the time is given in minutes, first convert it to hours by dividing by 60. If you want to work in drops rather than use a pump, see the drip rate calculator.

Calculate the infusion rate

Enter the volume and the time.

Calculate mL per hour

Infusions with a drug in the solution

When the prescription is given as an amount of drug per unit of time, you need the strength of the solution.

Rate (mL/h) = Dose per hour ÷ Concentration
Worked example: The prescribed dose is 20 mg per hour. The solution contains 4 mg/mL. Rate = 20 ÷ 4 = 5 mL/hour.

Dose per kg per minute

Some prescriptions are written as micrograms per kg per minute. First work out the dose per hour, then the rate.

mL/h = (micrograms/kg/min × kg × 60) ÷ micrograms/mL
Worked example: 5 micrograms/kg/min, the patient weighs 70 kg and the solution contains 1000 micrograms/mL (1 mg/mL).

5 × 70 × 60 = 21,000 micrograms per hour
21,000 ÷ 1000 = 21 mL/hour
Good to know: High-risk medicines (for example some that are given by pump) have local policies for double-checking and pump settings. Always follow them, and your course guidance.

Frequently asked questions

How do you calculate mL per hour?+

Divide the volume in mL by the time in hours. 500 mL over 4 hours gives 125 mL/hour.

What do I do if the time is in minutes?+

Divide the minutes by 60 to get hours before you calculate.

How do I calculate when the dose is given per kg per minute?+

Multiply the dose by the weight and by 60 to get the dose per hour, then divide by the concentration of the solution.

How is this different from drip rate calculations?+

Drip rate gives drops per minute for a gravity drip. A pump is set in mL per hour.

See all the drug calculation formulas →

Practise infusion calculations

Practise mL/h, pump settings and infusions with a drug in the solution. Dos is a practice app for drug calculations, with practice tests of ten questions, a built-in calculator next to each question and statistics per topic.